SKU: 11266624835

Shedding, Haaren

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Description

Shedding, HaarenReduzierter Haarausfall (MC5R) ist ein komplexes genetisches Merkmal, das alle Rassen betreffen kann und epistatische Wechselwirkungen mit FGF5 (Felllnge) und RSPO2 (Fellbeschaffenheit) hat, die ebenfalls die Haarmorphologie bei Hunden beeinflussen. Diese Loci haben aufgrund einer starken knstlichen Selektion fr das Fellphnotyp selektive Sweeps durchlaufen. Die MC5R Proteinsequenz ist evolutionr bei Sugetieren konserviert, und eine bestimmte Mutation

Reduzierter Haarausfall (MC5R) ist ein komplexes genetisches Merkmal, das alle Rassen betreffen kann und epistatische Wechselwirkungen mit FGF5 (Felllänge) und RSPO2 (Fellbeschaffenheit) hat, die ebenfalls die Haarmorphologie bei Hunden beeinflussen. Diese Loci haben aufgrund einer starken künstlichen Selektion für das Fellphänotyp selektive Sweeps durchlaufen. Die MC5R-Proteinsequenz ist evolutionär bei Säugetieren konserviert, und eine bestimmte Mutation verursacht eine konformationale Änderung in der Tertiärstruktur des Proteins, das an der Produktion von Talg beteiligt ist, was die Wasserabweisung und Thermoregulation beeinflusst und zu erhöhtem Haarausfall führen kann. Der Gentest kann das Ausmaß des Haarausfalls bei einem Hund offenbaren, was helfen kann, geeignete Hunde für die Zucht auszuwählen und den Haarausfall zu reduzieren. Da einzelne Gene nur Durchschnittswerte für den Haarausfall liefern, ist es fast notwendig, die Kombination der Gene MC5R und RSPO2 zu testen.

Im Folgenden sind 3 Tabellen aufgeführt, die das Ausmaß des Haarausfalls je nach Genotyp zeigen; die letzte veranschaulicht das Ausmaß des Haarausfalls je nach Genotypkombination von MC5R und RSPO2.

MC5R

Genotyp

Grad des Haarausfalls

SD/SD

Niedrig

SD/N

Moderat

N/N

Hoch

N – Wildtyp-Allel, SD - Variantenallel

Hunde mit einem oder zwei Kopien der Variantenallele verlieren weniger Haare als Hunde ohne Kopien.

RSPO2

Genotyp

Grad des Haarausfalls

F/F

Niedrig

F/N

Moderat

N/N

Hoch

F/F - Fellbeschaffenheit, N/F - Fellbeschaffenheit, N/N - unzureichendes Fell

KOMBINATION VON MC5R UND RSPO2

Genotyp MC5R

Genotyp RSPO2

Grad des Haarausfalls

SD/SD

F/F

0

SD/SD

F/N

1

SD/SD

N/N

2

SD/N

F/F

1

SD/N

F/N

2

SD/N

N/N

3

N/N

F/F

2

N/N

F/N

3

N/N

N/N

4

Grade des Haarausfalls: niedrig 0 < 1 < 2 < 3 < 4 hoch

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SKU: 11266624835

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Kindle Customer
Belleville, US
★★★★★ 4
Fun, Easy Read
Format: Kindle
A really fun, easy read! The main character was really likeable, and the male main characters were engaging and fun. Is this book going to change your life or reinvent literature? No. Is it an enjoyable read free from distracting errors that I plowed through in an afternoon? Yes. On to book two!
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Reviewed in the United States on December 20, 2024
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MM
Massapequa, US
★★★★★ 5
Knotty Omegas series is a work of art!!
Format: Kindle
A.J. Shirley has done it again. I was hesitant to read this book because of the premise of omegaverse, but I loved Shirley's Aegis Saga so much that I decided to give this a try. I finished it faster than any other book I've ever read. I fell in love with Serenity, her sharp wit, her creativity, and her ability to hope and love despite her horrible past. I loved witnessing her healing journey. Her chemistry and connection with the pack made my heart race. The men were incredibly lovable and snuggly. And the spice was SPICY. Buckle up.
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Reviewed in the United States on February 18, 2025
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vera price
Birmingham, US
★★★★★ 5
Knot their style
Format: Kindle
So I really enjoyed the story. I don’t really like dark omegaverse, surprisingly from the themes it did not go Dark. Instead, it stayed sweet. I like Serenity, you can tell just by the first scene that she was a fighter. She had to save her own life. Once she did save her own life she gets hit by a car. So then Pack Rhodes saves her life, I mean what do you do with a unconscious abused omega that you may or may not have hit with your car. Take her home of course. Loved this book and cant wait for the next one
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Reviewed in the United States on November 6, 2024
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Alicia L
Carnegie, US
★★★★★ 4
Cute read
Format: Kindle
Overall, this was a cute read. I liked the characters mostly. Remy was a bit ridiculous at points. Would consider reading more by this author.
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Reviewed in the United States on December 1, 2024
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Ashley Morgan
Belleville, US
★★★★★ 5
ABSOLUTELY A MUST for Omegaverse Girls!!!
I ABSOLUTELY LOVE Jillian West and her books!!! I’m so happy I already bought book two and now I have to buy the others for the Assurance Security series!! Not gonna lie Val kind of annoyed me at the beginning but she grew on me!! Her men are chef’s kisses!!! Holt annoys me some but I can let it slide. I already bought part two so I’m going to be reading that in between work phone calls!!!! DON’T TELL MY BOSS 😂😂😂😂
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Reviewed in the United States on September 30, 2025

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