SKU: 68484123862

B-Lokus (Siberian Husky)

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Description

B-Lokus (Siberian Husky)Das Gen TYRP1 (Tyrosinase verwandtes Protein 1) ist verantwortlich fr die schokoladen leberbraune Farbe bei Hunden. Diese Fellfarbe wird rezessiv vererbt. Es gibt 4 verschiedene Varianten am B Lokus beim Siberian Husky: bc, bs, bd und bh. Die Kombination von zwei rezessiven Allelen fhrt zu schokoladen leberbrauner Farbe (zum Beispiel zwei bc Allele oder ein bc und ein bs Allele). Da das TYRP1 Gen mit der Eumelaninproduktion verbunden ist, betrifft es

Das Gen TYRP1 (Tyrosinase verwandtes Protein 1) ist verantwortlich für die schokoladen-/leberbraune Farbe bei Hunden. Diese Fellfarbe wird rezessiv vererbt. Es gibt 4 verschiedene Varianten am B-Lokus beim Siberian Husky: bc, bs, bd und bh. Die Kombination von zwei rezessiven Allelen führt zu schokoladen-/leberbrauner Farbe (zum Beispiel zwei bc-Allele oder ein bc- und ein bs-Allele).

Da das TYRP1-Gen mit der Eumelaninproduktion verbunden ist, betrifft es nur Hunde, die den Genotyp E/E oder E/e am E-Lokus haben. Der B-Lokus beeinflusst auch die Farbe von Nase, Augen und Pfoten. Hunde mit dem Genotyp e/e produzieren nur Pheomelanin im Fell, aber die Produktion von Eumelanin in Nase, Augen und Pfoten ist nicht betroffen und daher vollständig vom B-Lokus kontrolliert. Je nach Genotypen der E- und B-Loci kann ein Hund ein gelbes Fell und eine braune Nase/Augen (e/e, b/b) oder ein schokoladenfarbenes Fell und eine braune Nase/Augen (E/e oder E/E und b/b) haben.

Der Test für den B-Lokus beim Siberian Husky besteht aus vier separaten Tests, um das Vorhandensein von rezessiven Allelen (bc, bs, bd und bh) zu überprüfen. Die Ergebnisse werden sowohl als kombinierte Ergebnisse als auch als Ergebnisse für jedes einzelne getestete Allel präsentiert.

Genotyp

Beschreibung

B/B:

Der Hund ist homozygot für das normale Allel; es sind keine rezessiven Allele für schokoladen-/leberbraun vorhanden, der Hund wird dominante Allele an die gesamte Nachkommenschaft übertragen.

B/b:

Der Hund ist heterozygot für schokoladen-/leberbraun, wenn eines der rezessiven Allele vorhanden ist (zum Beispiel Bc/bc, Bs/Bs, Bd/Bd), die braune Farbe wird nicht ausgedrückt, ein rezessives Allel kann an die Nachkommen übertragen werden.

b/b:

Der Hund ist schokoladen-/leberbraun (homozygot für die braune Farbe) in eumelaninpigmentierten Bereichen und trägt mindestens zwei rezessive Allele (identisch oder unterschiedlich), was bedeutet, dass der Hund entweder homozygot für ein Allel ist (zum Beispiel bc/bc, Bs/Bs, Bd/Bd) oder heterozygot für zwei Allele (zum Beispiel Bc/bc, Bs/bs, Bd/Bd).

Wenn zwei, drei oder vier Einzelkopievarianten von bc, bd, bs oder bh nachgewiesen werden, kann das Vorhandensein mehrerer Varianten auf einer Einzelkopie des Gens nicht ausgeschlossen werden. Daher könnte der Gesamtgenotyp des B-Lokus für einen Hund B/b oder b/b sein (der Hund kann schwarz oder braun erscheinen) und kann vom Labor ohne zusätzliche Tests der Eltern nicht bestimmt werden.

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SKU: 68484123862

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4.1 ★★★★★
Based on 15 reviews
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K
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Kit
San Leandro, US
★★★★★ 4
My dog loves this toy but…
Color: Grey Bear - Large
This toy has many pros and cons, but it’s my dogs all time favorite toy so I have to give it 4 stars. Pro:My German Shepard loves this toy, it has no squeaker and she hates squeakers, so she hasn’t tried to destroy it. It’s the perfect size for a large ball. She likes to throw her toys and this one has a pretty decent bounce to it so she can entertain herself. Cons: the inside is hard rubber, she likes to throw her toys and it hurts when she hits you with it or drops it on your feet. Also a huge hazard to windows and anything breakable.
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Reviewed in the United States on July 12, 2025
I
Verified Purchase
ingrid C
Phoenix, US
★★★★★ 5
Pretty awesome chew toy
Color: Grey Bear - Large
This toy is great!! I have a doodle that shreds everything in sight, including durable toys, but this one stood up to the Teddy test! He easily ripped off the ear/feet bits, but the fabric casing hasn’t come off after a week of play, and I expect the rubber toy inside will be even harder to break. This is a fairly heavy toy, so it makes a thunk when it drops and is probably not suitable for small dogs. It has a light squeak that is quiet and infrequent enough to not annoy me, and it’s pretty cute too!! it does get soaked in drool pretty fast (and takes forever to dry), but at this point i’m grateful it lasts long enough to get drooled on at all.
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Reviewed in the United States on September 30, 2025
A
Verified Purchase
a b
Waukegan, US
★★★★★ 3
less than 24 hours :/
Color: Grey Bear - Large, Color: Grey Bear - Large
smaller than i expected but had a strong interior that i was pleasantly surprised with. my lil lady very much enjoyed it, however it lasted less than 24 hours before the poor toy was skinned alive :( she loves plushies and she’s obsessed w his skin after tearing him apart. it does have a solid rubber interior that is still good as a toy, however i was hoping its skin would stay on longer than a day :( overall decent toy, 3 stars for being destroyed so quickly. wouldn’t recommend for strong chewers
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Reviewed in the United States on August 7, 2025
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Verified Purchase
Jen
Lexington, US
★★★★★ 5
Lasts long
Color: Panda Bear - Large
Perfect for super chewer dogs.
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Reviewed in the United States on May 14, 2026
M
Verified Purchase
Michelle B.
Waukegan, US
★★★★★ 4
Dachshund said “did I hear indestructible‽ Hold my ball”
Color: Grey Bear - Large
My 15lb Dachshund took this toy as a personal challenge. He heard me tell his human brother that it’s indestructible on the inside and said “hold my ball” promptly proceeding to schmurder the textile aspect of this adorable toy. I’d say it took him a total of 23 1/2 minutes to get to the center of this tootsie pop. I’m not even mad tho bc he had no interest in actually ingesting the outer part, and is totally into the inner toy, which is, for him, literally indestructible. It’s solid rubber, has a wild and fun bounce to it on multiple surfaces. Zodiac rates the squeak 10/10. It’s great especially for when I’m on a call or talking to someone in real life and can’t immediately throw said toy or pay complete attention to him. In conclusion: Your dog will probably love it, ((suggest to just keep an eye on them during the schmurder process and make sure you grab all the pieces that come off so none are swallowed)) Depending on your tolerance for squeaker pitch and frequency of squeak, it's a 4/10 in annoyance mostly bc it’s not a long drawn out squeak ((I can not tolerate those toys, they get “lost on top on my fridge” until I get up the courage to throw them out without him seeing)), it’s quick and requires a bit of effort to produce the sound however it’s a very high pitch squeak so it’s all up to your preference. I personally try to buy toys I can tolerate my dog loving on bc when he gets a new toy, it’s his favorite thing for a long time, like, it sleeps on the bed with us for the first month. Hope your fur child loves this as much as mine did. Not sure I’ll do the whole two in one toy thing again only he got through it so fast.
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Reviewed in the United States on December 25, 2025

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