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Description
Lighten & Lift Collection – 10% Off | StemulationSave 10% with the Lighten and Lift Collection by Stemulation. A blend of rare and high performing, high potency ingredients that firm and brighten the skin. The collection includes Elevate Eye Crme, Hi Impact Serum, and Boost Crme. The active ingredients in this collection comprise a combination of proteins and cytokine extracts from adult Mesenchymal stem cells, epidermal growth factors, Hyaluronic acid, Lactic acid, and an exceptional blend of
Save 10% with the Lighten and Lift Collection by Stemulation. A blend of rare and high-performing, high-potency ingredients that firm and brighten the skin. The collection includes Elevate Eye Crème, Hi Impact Serum, and Boost Crème. The active ingredients in this collection comprise a combination of proteins and cytokine extracts from adult Mesenchymal stem cells, epidermal growth factors, Hyaluronic acid, Lactic acid, and an exceptional blend of botanically-derived antioxidants. This is a powerful blend that both lightens skin tone and resists the formation of dark spots. This three-piece combo is powerful. It diminishes the appearance of puffiness and wrinkles while at the same time delivering superb plumping and hydration.The lightening of dark spots and dark circles requires consistency of use of the products.
Ingredients:
Elevate Eye Crème:
- Water (Aqua)
- Aloe Barbadensis (Aloe Vera) Leaf Juice
- Beta Glucan
- Saccharomyces Cerevisiae Extract
- Cyclopentasiloxane
- Dimethiconol
- Hydrolyzed Rice Bran Protein
- Oxido Reductases
- Glycine Soja (Soybean) Protein
- Dipeptide Diaminobutyroyl Benzylamide Diacetate
- Human Stem Cell Cultured Media
- Pentylene Glycol
- Dimethicone
- Allantoin
- Camellia Sinensis (Green Tea) Leaf Extract
- Vitis Vinifera (Grape) Seed Extract
- Vaccinium Myrtillus (Bilberry) Extract
- Silybum Marianum (Milk Thistle) Extract
- Pinus Pinaster Bark (Maritime Pine) Extract
- Ginkgo Biloba Extract
- Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
- Na Carbomer
- Tetrasodium Glutamate Copolymer
- Disodium EDTA
- Quaternium-15
Hi Impact Serum:
- Water/Aqua/Eau
- Pseudoalteromonas Exopolysaccharides
- Citric Acid
- Pentylene Glycol
- Sodium Ascorbyl Phosphate
- Niacinamide
- Lilium Candidum Leaf Cell Extract
- Sodium Hyaluronate
- Hexapeptide-33
- sH-Oligopeptide-1
- Hydrolyzed Hyaluronic Acid
- Sodium Lactate
- Disodium EDTA
- Ethylhexylglycerin
- Phenoxyethanol
Boost Crème:
- Water
- Aloe Barbadensis (Aloe Vera) Leaf Juice
- Caprylic Capric Triglycerides
- Beta Glucan
- Lactic Acid
- Vitus Vinifera (Grape) Seed Oil
- Cyclopentasiloxane
- Dimethiconol
- Glyceryl Stearate
- PEG-100 Stearate
- Glycerin
- Myristoyl Pentapeptide-8
- Hydrolyzed Rice Bran Protein
- Oxido Reductases
- Glycine Soja (Soybean) Protein
- Niacinamide
- Methylsulfonylmethane
- Panthenol
- Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
- Abrica Extract
- Camellia Sinensis (Green Tea) Leaf Extract
- Vitis Vinifera (Grape) Seed Extract
- Vaccinium Myrtillus (Bilberry) Extract
- Silybum Marianum (Milk Thistle) Extract
- Pinus Pinaster Bark (Maritime Pine) Extract
- Ginkgo Biloba Extract
- Sodium Lactate
- Tocopherol
- Ascorbyl Palmitate
- Xanthan Gum
- Steareth-21
- Laureth-4
- Disodium EDTA
- Fragrance (Parfum)
- Phenoxyethanol
- Ethylhexylglycerin
- Potassium Sorbate
- Sodium Benzoate
Features
- Includes: Elevate Eye Crème 0.5 fl. oz., Boos Crème 0.5 fl. oz., and Hi Impact Serum 0.5 fl. oz.
- Contains proteins, cytokine extracts from adult Mesenchymal stem cell, Hyaluronic Acid, and Lactic Acid.
- Puffiness wrinkles are both reduced while continued and consistent use lightens dark spots and dark circles.
- Lightens and brightens skin tone.
Using Stemulation Products
Using Stemulation® Products
Stemulation works for ALL skin types:
Stemulation works in reverse compared with most products on the market. Rather than the product dictating what the body needs, as do most products, Stemulation’s growth factors respond to the cells needs to help nurture and balance the health of the skin and tissue, thus addressing each individual need.
Ages 13 to 103 benefit:
Stemulation Luxury Skin Care offers exceptional quality ingredients designed to improve the overall health and vitality of the skin. Stemulation products contain numerous ingredients to slow the aging process. Nevertheless Stemulation has seen wonderful results with a variety of traditional troubled skin conditions and has made a tremendous impact on individuals as young as 13 suffering from breakouts by using the scrub, the serum and the boost. Since Stemulation has such an impact on the health and vitality of the skin, ages 13 to 103 will enjoy the improved texture, tone and healthy glow that Stemulation skin care produces. You can create or adjust your individual regimen will based on whether you are in the preventive or restorative stage in your skin care routine.
Use with other products?
YOU BETCHA!! Stemulation formulas are designed to augment and enhance a disciplined skin care routine. They do not interfere with ingredients in other products. Stemulation does recommended to apply its products first to cleansed skin and then proceed with your regular routine. For the best results, use Stemulation twice daily. If you use a retinol product or any glycolic, or lactic product is being used, it is not advisable to use the Boost Crème at the same time. The combination would be too aggressive and may cause irritation.
FAQ
Frequently Asked Questions
Is Stemulation safe?
Stemulation products have no known side effects. Neither we nor Stemulation give medical advice and if you are pregant or nursing, you should always consult your doctor for their medical opinion. However, the Stemulation medical advisory team and their research shows these products to bee non-invasive and safe to use while pregnant.
Why is Stemulation different?
Numerous skin care manufacturers use growth factors from a variety of sources. Stemulation, howoever, is the first product to use growth factors from the source, the stem cell itself. Like all things natural, fresh and new is usually better, and offers a higher degree of potency. Augmenting Stemulation's ground-breaking science, only the highest quality ingredients are used, producing products with exceptional efficacy providing users with a truly unique luxury skin care experience.
What can be expected, when beginning to use Stemulation products?
The mainstay of the Stemulation product line is the Boost Crème. It is the one product that you should not live without. You can add it to your existing regimen, or you can include it in developing a complete protocol. Using Stemulation Facial Serum, you'll notice a visible and tactile improvement to both the tone and texture of your skin. It will feel softer and smoother, and more vibrant and alive.
The Stemulation Boost Crème formulation opens pathways to allow the serum to penetrate more deeply into the dermis for more potent efficacy. Boost Crème will almost literally pull out impurities. When used as directed, the Boost Crème in combination with the Serum will tighten pores and improve skin texture within a week to 10 days. In the even you should experience any minor break out, continue with the products and the condition will improve in a few days, leaving beautiful results.
The Stemulation Boost Crème formulation opens pathways to allow the serum to penetrate more deeply into the dermis for more potent efficacy. Boost Crème will almost literally pull out impurities. When used as directed, the Boost Crème in combination with the Serum will tighten pores and improve skin texture within a week to 10 days. In the even you should experience any minor break out, continue with the products and the condition will improve in a few days, leaving beautiful results.
What about specific conditions?
Persons with rare skin conditions that include collagen over-production, or who are allergic to peptides, should avoid use.
Animal testing:
No Stemulation product is ever animal tested.
Does the scrub contain micro beads?
No. Stemulation used Diatomaceous Earth, which is a type of fossilized organic aquatic organisms, seaweek, and pumas. These ingredients are food grade, similar to toothpaste.
Is Stemulation organic?
Stemulation uses 85% to 87% organic and botanical ingredients. Some synthetic ingredients are used to enhance both stability and performance.
About Stem Cells
- Stemulation conditioned media was analyzed and tested at Stanford University for both its quality and its purity.
- The Stemulation advisory tem includes a renowned quadruple board certified cosmetic surgeon.
- Stemulation works with qualified pharmaceutical labs that have received GMP (good manufacturing practice) certifications.
- Stemulation new product development team includes two PhDs. &nbs;The original research work was conducted with UCI (University of California, Irvine) at the Bill and Susan Gross Stem Cell Research facility.
- Almost all Stemulation products use aloe as the base due to its anti-inflammatory properties and its ability to help promote healing.
- Stemulation is laser-focused on our their formulations with a goal of using as many botanical and natural ingredients as possible to enrich the products. The botanicals used are filled with nutrients and anti-oxidants that help support the effects of the stem cell science. Stemulation is real science with real results –– a true confluence of science and nature.
Stem Cells and Stemulation®:
Stem cells are used to produce growth factors, cytokines and proteins through a cell proliferation process to create the conditioned media used in Stemulation® formulas. Conditioned media is the fluid that contains the growth factors, cytokines and peptides once the stem cells are removed. Conditioned media is the active ingredient in Stemulation.
Growth factors, cytokines and peptides:
Put simply, growth factors are the "messenger signals" that tell body cells to respond. As the “EMT of the bodyâ€, Mesenchymal stem cells tend to be drawn to the location of a trauma and begin a cell proliferation process that produces cytokines (aka peptides), growth factors, and proteins that direct the body’s response from the nearby and surrounding cells. Stemulation® has enabled the same effect with the stem cells bypassed by utilizing the conditioned media that has been produced by the stem cells.
Stem Cell Origin:
Stemulation® uses only donor-certified stem cells sourced from GMP Medical Laboratories. The stem cells are derived from donated bone marrow and are non-embryonic. These stem cells are the are the identical quality and sources that supply cells for research and transplantation.
Types of Stem Cells:
Only Mesenchymal Stem Cells are used because they are pluripotent. Mesenchymal stem cells are from bone marrow but more specifically, pluripotent cells are cells that are capable of differentiating into one of many cell types such as skin, bone, tissue and blood.
Mesenchymal stem cells in the body:
These are the "medical signaling" cells of the body that act as the "emergency medical team" of they body. They function to direct the body's healthy cells to respond to any deficiency or trauma.
Stemulation® products CONTAIN NO STEM CELLS.
Stem cells are unable to live outside of a carefully controlled environment - such as the body or in the lab. Also, the molecular size of stem cells is too large to be absorbed by the skin. It's simply not possible, and any product claiming to contain actual stem cells is providing misinformation.
About Stemulation
Laurie Nicoll
Founder
Michelle Kleker
Executive Vice President
Prior to founding Stemulation, Laurie Nicoll's background included tenure at a stem cell research company. In 2008 she was inspired to harness the power and science of stem cells in a revolutionary way. She became driven to find a method by which to capture the healing properties of stem cells for use aesthetically. Additionally fueled by her personal skin challenges, Ms. Nicoll gathered a team of experts to accomplish her goal. The team comprised doctors and scientists each of whom specialized in the field of stem cell therapies, and from such renowned institutions as University of Southern California, Irvine’s well-known Bill and Susan Gross Stem Cell Research Center. After two years of research and development the culmination was the creation of Stemulation Skin Care.
The Stemulation management team as a combined business background of 50 years' management. The Stemulation Board of Directors comprises medical, aesthetic, retail, cosmetic industry professionals, and luxury resort executives. The Board brings in experience from leaders at world-renowned firms including Revlon, Dauphin, Guinot, Lancome, and Hyatt International.
Founder's Statement
"Stemulation Skin Care is committed to creating exceptional and ethically-produced skin care products. Giving back is central to our corporate culture. The Footprints Foundation was formed to leave a legacy, as our footprints in the sand remind us we can’t make it alone. Through The Footprints Foundation, Stemulation supports a variety of philanthropic organizations with a focus on empowering women and serving our community. Character defines you personally and professionally. We strive to always live life honestly, ethically and fearlessly with passion, tolerance, and compassion, above all else." - Laurie Nicoll
Some Important Points
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy
4.7 ★★★★★
Based on 704 reviews
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Product Reviews
★★★★★ 5
Wonderful face cleanser
Style: Tolerance Daily Foaming Facial Cleanser
The best product I have found for cleansing my make up off. I have rosacea and I find this to be so gentle on my face.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 27, 2026
★★★★★ 5
A foaming cleanser that doesn't dry out my skin!
Style: Tolerance Daily Foaming Facial Cleanser
I have very dry, reactive skin and initially looked past this face wash because it is foaming which is usually a no-go for my skin. I am pleasantly surprised with how well my skin tolerated this product. No dryness or irritation and my face felt clean. I also love that it is fragrance free because fragrances seem to really irritate my skin and who needs to smell their face wash? I am happy to say this is another great product from Avene!
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Reviewed in the United States on April 2, 2026
★★★★★ 5
Gentle cleanser for dry and sensitive skin.
Style: Tolerance Daily Foaming Facial Cleanser, Style: Tolerance Daily Foaming Facial Cleanser
I have dry and sensitive skin, and this cleanser has worked very well for me. It is very gentle on the skin and has not caused any irritation.
The texture is light and foamy, it spreads easily across the face and rinses off without leaving any residue. After using it, my skin feels clean, soft, and comfortable, without any tightness.
The size is quite large, which I find great because it lasts a long time with daily use.
Overall, a simple but very pleasant cleanser for sensitive skin.
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Reviewed in the United States on April 13, 2026
★★★★★ 5
I Just Want to Help People With Skin Problems!
Style: Tolerance Control Soothing Skin Recovery Cream
I so wish I had known about this skincare line a long time ago, but just glad I did find it at all. I have rosacea (including ocular rosacea) diagnosed by a dermatologist. I had been through all the typical stores and websites, trying so many things over the last 15 years. Yes, most were supposed to be for people with skin problems. EVERY SINGLE TIME I tried something, within five minutes, my skin was bright red. My skin reacted to EVERYTHING. I started to believe there was not one single product on the entire planet that my skin would not react to! It was so frustrating. Purchase, fail, repeat. Thing is, I had tried their spring water spray. I sort of ignored all the other products until I was talking to someone randomly and they asked if I had tried Avene. Honestly I decided maybe this was providence and that I had better try it just to be on the safe side. What would life be like if I had ignored their advice and not tried it? If this company ever goes out of business, I will have to live with terrible skin because I already know there is nothing else out there. I had read a review whereby someone said their doctor told them the longer they used the products, the better their skin would get. This is completely true. But even initially, all I cared was that I could relieve the dryness with SOMETHING that did not turn my skin RED IMMEDIATELY! Even THAT, I would have been happy with! Now for the rest of the benefits. I had the good intuition to purchase two of these when they were on sale. I am so glad I did. I use it like crazy every chance I get. It just feels so good going on and I like touching my skin even after the product dissipates. No redness, no irritation, it actually CALMS my skin. And makes it like, well, "real skin." I'm glad I also got the thicker version in the tube, Cicalfate. This is my go-to for dryer areas and in the winter. The two together along with the water spray, if you like to use something like that, are a great overall program. Definitely other things I would like to try. Again, my goal was to help others who have skin problems because everything else out there has no concept whatsoever of calming the skin, but the exact opposite -- irritating it worse (even if those products are supposed to help with redness or irritation). And I felt the company truly deserves a shout-out because they GET IT when it comes to skincare products. Whatever they've done, they are experts, far more than all the other skincare lines and I don't care how long those have been around. If it doesn't immediately tell you your skin "likes it" and shows it by not reacting or immediately getting better, why on earth would you pay your hard-earned money to buy it and keep using it? It's worth every penny, don't bat an eyelash, your skin is worth that and more. If it's on sale, get a lot of it because trust me, you are going to want and need it. You will be so glad you got more than one. I definitely am! THANK YOU, AVENE, WE LOVE YOU HERE IN AMERICA! YOU UNDERSTAND SKINCARE LIKE NO OTHER COMPANY!
Update: Wanted to comment that I'm still so grateful for a product that does FAR MORE than what you expect! I recently bought more. I watch my skin calm down the minute I put it on. I don't know entirely how the ingredients do what they do, but to the company ... please don't fix what isn't broken! Too many companies have a good thing and then change it. Please don't, the products are perfect and far beyond expectation! I also wanted to mention it seems the Tolerance tube will get EVERY LAST BIT out, you won't be wondering if there is anything left you are discarding. The Cicalfate tube is a bit different, it's more like a squeeze tube. But I feel I can still get the product out to use it all. That said, you get your money's worth. I'm also starting to use the Cicalfate on my hands in the winter, too (which are sadly starting to show my age). But this product line has literally CHANGED MY LIFE! BUY IT, it's the REAL DEAL!
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Reviewed in the United States on August 10, 2025
★★★★★ 5
Love this cream
Style: Tolerance Control Soothing Skin Recovery Cream
I absolutely love the Avène Tolerance Control Soothing Skin Recovery Cream — it’s become a sanctuary for my sensitive skin. From the very first application, I noticed how calming and gentle it feels. The texture is rich yet lightweight, absorbing beautifully without any greasiness.
This cream has been a game‑changer for days when my skin feels irritated, reactive, or overwhelmed. It instantly soothes redness and discomfort, and over time my skin feels stronger, more balanced, and resilient. What really stands out is how comfortable and nourished my skin feels all day long — no tightness, no irritation, just pure relief.
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Reviewed in the United States on February 26, 2026