SKU: 25810381694

ITPRIPL1 His Tag Protein, Human

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Description

ITPRIPL1 His Tag Protein, HumanProduct Specification Species Human Synonyms Inositol 1,4,5 trisphosphate receptor interacting protein like 1; ITPRIPL1; KIAA1754L; CD3L1 Accession Q6GPH6 Amino Acid Sequence His25 Gly103, with C terminal His Expression System HEK293 Molecular Weight 10. 1 KDa Purity 95% by SDS PAGE Endotoxin <1EU g Conjugation Unconjugated Tag His Tag Physical Appearance Lyophilized Powder Storage Buffer PBS, pH7. 4. Reconstitution Always centrifuge tubes before

Product Specification


Species Human
Synonyms Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1; ITPRIPL1; KIAA1754L; CD3L1
Accession Q6GPH6
Amino Acid Sequence His25-Gly103, with C-terminal His
Expression System HEK293
Molecular Weight

10.1 KDa

Purity

＞95% by SDS-PAGE
Endotoxin <1EU/μg
Conjugation Unconjugated
Tag His Tag
Physical Appearance Lyophilized Powder
Storage Buffer PBS, pH7.4.
Reconstitution
  • Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
  • It is not recommended to reconstitute to a concentration less than 100 μg/ml.
  • Dissolve the lyophilized protein in distilled water.
  • Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Stability & Storage
  • Lyophilized protein should be stored at ≤ -20℃, stable for one year after receipt.
  • Reconstituted protein solution can be stored at 2-8℃ for 2-7 days.
  • Aliquots of reconstituted samples are stable at ≤ -20℃ for 3 months.

Background

Cancer immunotherapy has transformed treatment possibilities, but its effectiveness differs significantly among patients, indicating the presence of alternative pathways for immune evasion. Here, we show that ITPRIPL1 functions as an inhibitory ligand of CD3ε, and its expression inhibits T cells in the tumor microenvironment. 1,4,5-triphosphate receptor-interacting protein-like 1 (ITPRIPL1), a natural CD3 ligand, to evade immune surveillance and promote tumor growth. ITPRIPL1, is also a remarkable NSCLC biomarker. Detecting ITPRIPL1 in tumors can contribute to better diagnosis, CD8 positive T cell infiltration revelation, disease progression surveillance, and prognosis prediction.

Shipping Notes
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Exchange/Return Notes
  • We offer a 30-day return/exchange service after receiving.
  • Final sale items are not eligible for returns or exchanges.
  • To process your return/exchange, please contact us at [email protected]
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SKU: 25810381694

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4.2 ★★★★★
Based on 2301 reviews
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Verified Purchase
Gar
San Leandro, US
★★★★★ 5
Easy to apply and rubs in quick
Works great
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Reviewed in the United States on June 8, 2026
N
NN
Lexington, US
★★★★★ 5
Lasts a long time
I've been using this sunscreen on myself and two kids almost daily for the past two months or so. And we are still not even half through one bottle - there's plenty of product in there and you only need a little bit. I like that this lotion absorbs fast and doesn't wear off for a very long time. It has a mild fragrance and a bit of an oily texture. But it does a great job protecting skin from the sun.
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Reviewed in the United States on May 30, 2026
S
Samantha Villamor
Battle Creek, US
★★★★★ 5
Quality sunscreen
Works just as expected. Don't apply too much at once, just enough for thin layer so it doesn't just sit on top of the skin and actually absorbs properly. Not too oily. The smell is pleasant and not too strong. Definitely need to reapply as directed for maximum protection. Pretty easy to open with one hand if needed, which is an added plus.
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Reviewed in the United States on May 16, 2026
M
Verified Purchase
Michelle
Lowell, US
★★★★★ 1
Burns eyes
I am sad to say it burns eyes. The old formula did not. This one does. My eyes are burning so bad. I can’t even keep them open to read a book. I see the trick now. Bottle reads won’t run into eyes, not won’t sting eyes.
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Reviewed in the United States on May 15, 2026
S
SummerT
Los Angeles, US
★★★★★ 5
Tears free sunscreen
Perfect for my little ones- busy at sports, this one holds sweat and tears! It does require you to apply with patience otherwise they are white ghosts until it fully absorbs but no tears and they do sometimes wiggle so it goes everywhere lol Easy to wash off and does its job protecting their kids skin nicely from the vicious sun - I would recommend!
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Reviewed in the United States on March 20, 2026

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