SKU: 42034761994

TIMP-1 Protein, Mouse

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Description

TIMP-1 Protein, MouseProduct Specification Species Mouse Synonyms TIMP1, CLGI, TIMP Accession P12032 Amino Acid Sequence Cys25 Arg205, with C terminal His Tag Expression System HEK293 Molecular Weight 25 30kDa (Reducing) Purity 95% by SDS PAGE and HPLC. Endotoxin <0. 1EU g Tag His Tag Physical Appearance Lyophilized Powder Storage Buffer PBS, pH7. 4 Reconstitution Reconstitute at 0. 1 1 mg ml according to the size in ultrapure water after rapid centrifugation. Stability &

Product Specification


Species Mouse
Synonyms TIMP1, CLGI, TIMP
Accession P12032
Amino Acid Sequence Cys25-Arg205, with C-terminal His Tag
Expression System HEK293
Molecular Weight

25-30kDa (Reducing)

Purity >95% by SDS-PAGE and HPLC.
Endotoxin <0.1EU/μg
Tag His Tag
Physical Appearance Lyophilized Powder
Storage Buffer PBS, pH7.4
Reconstitution Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Reference

1、Hornebeck W. (2004) Down-regulation of tissue inhibitor of matrix metalloprotease-1 (TIMP-1) in aged human skin contributes to matrix degradation and impaired cell growth and survival. Pathol Biol. 51(10): 569-573.
2、Soini Y. et al. (2001) Expression of MMP2, MMP9, MT1-MMP, TIMP-1, and TIMP2 mRNA in valvular lesions of the heart. J Pathol. 194(2): 225-231.

Background

TIMP metallopeptidase inhibitor 1 is also known as TIMP1, a tissue inhibitor of metalloproteinases, is a glycoprotein that is expressed from the several tissues of organisms. TIMP1 is a glycoprotein with a molecular mass of 28 kDa produced by a wide range of cell types. Tissue inhibitor matrix metalloproteinase 1 (TIMP1), which belongs to TIMP gene family, is a natural inhibitor of the matrix metalloproteinases (MMPs). Tissue inhibitor of metalloproteinases 1 (TIMP1) was the secreted factor with the strongest male-biased expression in patient-derived pancreatic tumors. Male-specific up-regulation of systemic TIMP1 was demonstrated in PC mouse models and patients.

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SKU: 42034761994

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PrimoCat
Carnegie, US
★★★★★ 5
Difficult to destroy. Bounce really high.
Style: Squeaker, Size: Small (2 Pack)
Bought as a gift for a friend's small dog who dismantles tennis balls. He loves them. I have many years of experience with the product (in a larger size) for my big dog. He always had one either in his mouth or near him. They are pretty much indestructible.
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Reviewed in the United States on May 13, 2026
M
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Majesty
Cuba, US
★★★★★ 4
High quality, wish it was just a little smaller
Style: Squeaker, Size: Small (2 Pack)
Love these. My dogs would play ball all day if I let them. These are very durable and bouncy. Love that it’s washable. They would chew up the small “tennis” balls to pieces so I love that they can’t destroy these. My only criticism is I wish these were just a little smaller (like the size of the small Kong tennis balls). My dogs can carry it in their tiny mouths but they can’t get their mouth around it enough to chew it to get the squeaker to squeak, which is their favorite thing.
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Reviewed in the United States on January 5, 2026
C
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CA Goose
Natrona Heights, US
★★★★★ 5
Perfect for little dogs
Style: Ultra, Size: Small (2 Pack)
Perfect size for my 13 pound chihuahua mix. Great bounce and quality feel. Definitely worth it.
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Reviewed in the United States on March 26, 2026
A
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Amazon Customer
Houston, US
★★★★★ 5
The perfect ball for a small to medium dog.
Style: Ultra, Size: Small (2 Pack)
My dog's favorite ball. Perfect size for playing catch and return for a small dog. She loves to chew on the ball. Very durable she has not been able to shred the ball. A great entertainment value. This ball does not squeak.
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Reviewed in the United States on February 27, 2026
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Kristy Kelly
Louisville, US
★★★★★ 5
High quality, dogs love them
Style: Ultra, Size: Medium (1 Pack)
My dogs are obsessed with these balls! We've had them for months and they're still good as new. High quality!
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Reviewed in the United States on April 5, 2026

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