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Description
CD50 Recombinant Rabbit mAb (S-666-37)Product Specification Host Rabbit Antigen CD50 Synonyms Intercellular adhesion molecule 3, ICAM 3, CDw50, ICAM R, ICAM3 Immunogen Synthetic Peptide Location Membrane Accession P32942 Clone Number S 666 37 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P, IP Reactivity Hu Predicted Reactivity Cz Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05%BSA,
Product Specification
| Host | Rabbit |
| Antigen | CD50 |
| Synonyms | Intercellular adhesion molecule 3, ICAM-3, CDw50, ICAM-R, ICAM3 |
| Immunogen | Synthetic Peptide |
| Location | Membrane |
| Accession | P32942 |
| Clone Number | S-666-37 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, IP |
| Reactivity | Hu |
| Predicted Reactivity | Cz |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | |
| IHC | 1:500 | |
| IP | 1:50 |
Background
Intercellular adhesion molecule 3 (ICAM3) also known as CD50 (Cluster of Differentiation 50), is a protein that in humans is encoded by the ICAM3 gene. The protein is constitutively expressed on the surface of leukocytes, which are also called white blood cells and are part of the immune system. ICAM3 mediates adhesion between cells by binding to specific integrin receptors. It plays an important role in the immune cell response through its facilitation of interactions between T cells and dendritic cells, which allows for T cell activation. ICAM3 also mediates the clearance of cells undergoing apoptosis by attracting and binding macrophages, a type of cell that breaks down infected or dying cells through a process known as phagocytosis, to apoptotic cells.
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Exchange/Return Notes
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