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Description
FGL2 His Tag Protein, MouseProduct Specification Species Mouse Synonyms FGL2, T49, pT49 Accession P12804 Amino Acid Sequence Pro197 Pro432, with C terminal 8*His PVQHLIYKDCSDHYVLGRRSSGAYRVTPDHRNSSFEVYCDMETMGGGWTVLQARLDGSTNFTREWKDYKAGFGNLEREFWLGNDKIHLLTKSKEMILRIDLEDFNGLTLYALYDQFYVANEFLKYRLHIGNYNGTAGDALRFSRHYNHDLRFFTTPDRDNDRYPSGNCGLYYSSGWWFDSCLSANLNGKYYHQKYKGVRNGIFWGTWPGINQAQPGGYKSSFKQAKMMIRPKNFKPGGGSHHHHHHHH Expression System HEK293 Molecular Weight 38 43kDa Purity >95% by SDS
Product Specification
| Species | Mouse |
| Synonyms | FGL2, T49, pT49 |
| Accession | P12804 |
| Amino Acid Sequence | Pro197-Pro432, with C-terminal 8*His PVQHLIYKDCSDHYVLGRRSSGAYRVTPDHRNSSFEVYCDMETMGGGWTVLQARLDGSTNFTREWKDYKAGFGNLEREFWLGNDKIHLLTKSKEMILRIDLEDFNGLTLYALYDQFYVANEFLKYRLHIGNYNGTAGDALRFSRHYNHDLRFFTTPDRDNDRYPSGNCGLYYSSGWWFDSCLSANLNGKYYHQKYKGVRNGIFWGTWPGINQAQPGGYKSSFKQAKMMIRPKNFKPGGGSHHHHHHHH |
| Expression System | HEK293 |
| Molecular Weight | 38-43kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference |
1、Feng Y. et al. (2020) Fibrinogen-Like Protein 2 (FGL2) is a Novel Biomarker for Clinical Prediction of Human Breast Cancer. Med Sci Monit. 26: e923531. 2、Hou X X. et al. (2021) Regulatory T cells induce polarization of pro-repair macrophages by secreting sFGL2 into the endometriotic milieu. Commun Biol. 4(1): 499. |
Background
Fibrinogen-like protein 2 (FGL2) is a member of the fibrinogen-like protein family and possesses important regulatory functions in both innate and adaptive immune responses. Fibrinogen-like protein 2 (FGL2) exists in both soluble and membrane forms. Soluble fibrinogen-like protein 2 (sFGL2) has been recently identified as a novel effector molecule of Tregs and plays a pivotal role in regulating both innate and adaptive immunity. FGL2 mediates its immunosuppressive activity by binding to inhibitory FcγRIIB (CD32B) receptors expressed by antigen presenting cells (APC), including dendritic cells (DC) and B cells, and thus sFGL2 may inhibit the maturation of DC, resulting in the suppression of effector T cell responses and inducing apoptosis of B cells. However, nothing is known about sFGL2 and its potential roles in endometriosis.
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4.8 ★★★★★
Based on 20 reviews
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Product Reviews
★★★★★ 3
Cute bag, cheap chain
Color: Stain Navy Blue1
Very cute, very spacious. I was able to keep my phone and a mini sewing kit with me but the chain broke 10 minutes into the reception while standing in line for the buffet. The whole point in buying this was so I could keep my stuff with me and not risk putting it on a table to the side of the dance floor after dinner. The bag itself is cute and I can get a replacement chain but it's unfortunate that I have to spend more money to make it work.
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Reviewed in the United States on March 24, 2026
★★★★★ 5
Stylish and size
Color: Black
Super cute and perfect size for evening outings
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Reviewed in the United States on April 10, 2026
★★★★★ 5
Trendy and great quality
Color: Brown
Super nice quality for price, holds more than looks like and comes with lovely zip pouch for stray things or could work as wallet. Recommend tying scarf around handle for color!
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Reviewed in the United States on October 28, 2025
★★★★★ 5
Stylish and unique
Color: White
I love this bucket purse. It looks just like the purse I saw a YouTube fashion influencer using, but costs a lot less. Nice quality.
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Reviewed in the United States on January 13, 2026
★★★★★ 4
Love the look and the size
Color: Brown
Great size for a small bag. I wanted something that would carry a water bottle, phone, card case, keys and sunglasses. Just my essentials but did not want to carry my BIG bag this summer. This was a cute alternative. Not real leather but looks like it is. Quality is pretty good- wish it was real leather though, but the functionality of the staps is what really does it for me. It's been a perfect size and shape for me. Easy to dress up or down.
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Reviewed in the United States on July 3, 2025