Pay in installments of $25.00 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Jul 23 - Jul 28
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
Alexa Fluor® 647 Rat Anti-Mouse CD185 Antibody (S-R600)Product Specification Host Rat Antigen CD185 Synonyms C X C chemokine receptor type 5; CXC R5; CXCR 5; Burkitt lymphoma receptor 1 homolog; Blr1; Gpcr6; Cxcr5 Location Cell membrane Accession Q04683 Clone Number S R600 Antibody Type Rat mAb Isotype IgG2b,k Application FCM Reactivity Ms Positive Sample C57BL 6 mouse splenocytes Purification Protein G Concentration 0. 05mg ml Conjugation Alexa Fluor 647 Physical Appearance Liquid Storage Buffer PBS, 25%
Product Specification
| Host | Rat |
| Antigen | CD185 |
| Synonyms | C-X-C chemokine receptor type 5; CXC-R5; CXCR-5; Burkitt lymphoma receptor 1 homolog; Blr1; Gpcr6; Cxcr5 |
| Location | Cell membrane |
| Accession | Q04683 |
| Clone Number | S-R600 |
| Antibody Type | Rat mAb |
| Isotype | IgG2b,k |
| Application | FCM |
| Reactivity | Ms |
| Positive Sample | C57BL/6 mouse splenocytes |
| Purification | Protein G |
| Concentration | 0.05mg/ml |
| Conjugation | Alexa Fluor® 647 |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 25% Glycerol, 1% BSA, 0.3% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied. |
Dilution
| application | dilution | species |
| FCM | 5μl per million cells in 100μl volume | Ms |
Background
CD185, also known as CXCR5 or Burkitt lymphoma receptor 1 (BLR1), is a G protein-coupled receptor with seven transmembrane regions. It belongs to the CXC chemokine receptor family and specifically binds to the chemokine CXCL13. This protein is crucial for the migration of B cells into B cell follicles in the spleen and Peyer's patches, and it is also essential for the function of follicular helper T cells. CD185 is expressed in mature B cells, follicular helper T cells, and certain types of lymphoma, including Burkitt's lymphoma. Additionally, it may play a role in maintaining cardiac structure under pressure overload and in the formation of ectopic mucosa-associated lymphoid tissue during chronic inflammation.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy