SKU: 99486921361

CD44/CDw44/ECMR-III His Tag Protein, Human

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Description

CD44/CDw44/ECMR-III His Tag Protein, HumanProduct Specification Species Human Synonyms CD44,CDW44,CSPG8,ECMR III,HCELL,HUTCH I,IN,LHR,MC56,MDU2,MDU3,MIC4,Pgp1 Accession P16070 1 Amino Acid Sequence Gln21 Pro220, with C 8*His Expression System HEK293 Molecular Weight 43 60kDa (Reducing) Purity 95% by SDS PAGE Endotoxin <0. 1EU g Conjugation Unconjugated Tag His Tag Physical Appearance Lyophilized Powder Storage Buffer PBS, pH7. 4. Reconstitution Reconstitute at 0. 1 1mg ml according to the

Product Specification


Species Human
Synonyms CD44,CDW44,CSPG8,ECMR-III,HCELL,HUTCH-I,IN,LHR,MC56,MDU2,MDU3,MIC4,Pgp1
Accession P16070-1
Amino Acid Sequence Gln21-Pro220, with C-8*His
Expression System HEK293
Molecular Weight 43-60kDa (Reducing)
Purity >95% by SDS-PAGE
Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag His Tag
Physical Appearance Lyophilized Powder
Storage Buffer PBS, pH7.4.
Reconstitution Reconstitute at 0.1-1mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Reference

1.Review Front Cell Neurosci. 2015 May 7;9:175. eCollection 2015.

Background

CD44 is a type I transmembrane protein and a member of the cartilage link protein family. Human CD44 has a 20 amino acid (aa) signal sequence, an extracellular domain (ECD) with a 100 aa hyaluronan-binding disulfide-stabilized link region and a 325-530 aa stem region, a 21 aa transmembrane domain, and a 72 aa cytoplasmic domain. CD44 is the major surface hyaluronan (HA) receptor implicated in intercellular and cell-matrix adhesion, cell migration and signaling. CD44 participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms.

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SKU: 99486921361

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