SKU: 66993749813

Dulbecco's Modified Eagle's Medium (DMEM) - Modification 15

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Description

Dulbecco's Modified Eagle's Medium (DMEM) - Modification 15Dulbecco's Modified Eagle's Medium (DMEM) Modification 15 containing high glucose and L glutamine, but not containing sodium pyruvate or sodium bicarbonate, is a specialized formulation widely utilized in cell culture due to its tailored nutrient profile. This medium provides a high concentration of glucose, serving as a vital energy source, particularly beneficial for rapidly proliferating cells and those requiring high metabolic activity. The

Dulbecco's Modified Eagle's Medium (DMEM) - Modification 15 containing high glucose and L-glutamine, but not containing sodium pyruvate or sodium bicarbonate, is a specialized formulation widely utilized in cell culture due to its tailored nutrient profile. This medium provides a high concentration of glucose, serving as a vital energy source, particularly beneficial for rapidly proliferating cells and those requiring high metabolic activity. The inclusion of L-glutamine, an essential amino acid, supports protein synthesis and cellular metabolism, ensuring optimal growth and viability of cultured cells.

The absence of sodium pyruvate in this DMEM (Modification 15) is advantageous for specific experimental setups where the presence of pyruvate could interfere with metabolic studies or cellular processes under investigation. Similarly, the exclusion of sodium bicarbonate allows for precise pH control, especially in closed systems or during transport where CO2 levels cannot be regulated. This makes the medium highly adaptable for a variety of research conditions and applications.

Key applications of DMEM - Modification 15 include:

  • Metabolic Studies: Ideal for experiments focusing on cellular metabolism without the confounding effects of pyruvate.
  • Transport and Storage: Suitable for use in conditions where CO2 regulation is not feasible, maintaining stable pH levels.
  • Protein Expression: Supports high-density cell cultures for the production of recombinant proteins.
  • Cancer Research: Facilitates the growth of cancer cell lines that exhibit high metabolic rates.
  • Stem Cell Culture: Provides a nutrient-rich environment for the proliferation and differentiation of various stem cell types.

Disclaimer: Results may vary depending on specific cell lines, specifications, and experimental conditions. Consult with cell culture specialists and review comprehensive literature to tailor its use to your specific research needs.

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SKU: 66993749813

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4.5 ★★★★★
Based on 19 reviews
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Product Reviews
C
Verified Purchase
crackinwall
Birmingham, US
★★★★★ 5
Dog loves snakey!
Style: Rainbow Snake
Is great for play loving dog..with gentle mouth. Surprisingly, it has really held up after tons of tugging. I didn’t think it would bc is not heavy duty material or stitching, rather is soft & light weight. Has plenty of squeakers too! - Darker colors would be nice! Human preference. :)
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 20, 2024
B
Verified Purchase
Beverly Quarles
Birmingham, US
★★★★★ 3
Poor quality and materials
Style: Rainbow Snake
I bought this for my 8 week old German Shorthaired Pointer puppy. Within 24 hours the majority of the squeakers were dead, and about 1/3 of the squeakers had been removed. The material is not strong and easily ripped open. I gave 3 stars because my puppy liked the toy, but the quality was not good. I expect to be throwing this toy in the garbage by the end of the week.
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Reviewed in the United States on December 29, 2025
V
Verified Purchase
Veronica M
Phoenix, US
★★★★★ 4
Here for a good time, not a long time
Style: Rainbow Snake, Style: Rainbow Snake
Our puppy loved his snake. Within 10 minutes he already had one of the squeakers out! Not very good quality for the price in my opinion. 6 weeks later and every squeaker is out and all the stuffing! He still plays with it even though it is just a piece of cloth now. I gave it 4 stars because he still loves it.
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Reviewed in the United States on March 15, 2026
C
Verified Purchase
Carolann Gemski
Boise, US
★★★★★ 1
Quality has gone down from previous ones
Style: Rainbow Snake
I've bought two of these - my dog goes crazy for them! She's only 12 lbs and not a big chewer. The first one lasted a few years, before the squeakers gave out and the seams opened (I got that one at Marshall's). The second one I got more recently on Amazon. It fell apart in just a few weeks.
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Reviewed in the United States on September 11, 2025
A
Verified Purchase
Amazon Customer
Pawtucket, US
★★★★★ 2
Don’t bother spending your money
Style: Rainbow Snake
This dog toy is definitely not worth the money. It is cheaply made and the squeakers are so close to surface that my dog will destroy it in no time. There is hardly any filling in the toy. I do not recommend!
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Reviewed in the United States on October 20, 2024

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