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Description
FGL2 His Tag Protein, CynomolgusProduct Specification Species Cynomolgus Synonyms FGL2, T49, pT49 Accession A0A2K5WID3 Amino Acid Sequence Pro204 Pro439, with C terminal 8*His PVQHLIYKDCSDYYAIGKRSSETYRVTPDPKNRSFEVYCDMETMGGGWTVLQARLDGSTNFTRTWQDYKAGFGNLRREFWLGNDKIHLLTKSKEMILRIDLEDFNGVKLYALYDQFYVANEFLKYRLHVGNYNGTAGDALRFNKHYNHDLKFFTTPDKDNDRYPSGNCGLYYSSGWWFDACLSANLNGKYYHQKYRGVRNGIFWGTWPGVSEAHPGGYKSSFKEAKMMIRPKHFKPGGGSHHHHHHHH Expression System HEK293 Molecular Weight 36 42kDa Purity >95%
Product Specification
| Species | Cynomolgus |
| Synonyms | FGL2, T49, pT49 |
| Accession | A0A2K5WID3 |
| Amino Acid Sequence | Pro204-Pro439, with C-terminal 8*His PVQHLIYKDCSDYYAIGKRSSETYRVTPDPKNRSFEVYCDMETMGGGWTVLQARLDGSTNFTRTWQDYKAGFGNLRREFWLGNDKIHLLTKSKEMILRIDLEDFNGVKLYALYDQFYVANEFLKYRLHVGNYNGTAGDALRFNKHYNHDLKFFTTPDKDNDRYPSGNCGLYYSSGWWFDACLSANLNGKYYHQKYRGVRNGIFWGTWPGVSEAHPGGYKSSFKEAKMMIRPKHFKPGGGSHHHHHHHH |
| Expression System | HEK293 |
| Molecular Weight | 36-42kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference |
1、Feng Y. et al. (2020) Fibrinogen-Like Protein 2 (FGL2) is a Novel Biomarker for Clinical Prediction of Human Breast Cancer. Med Sci Monit. 26: e923531. 2、Hou X. et al. (2021) Regulatory T cells induce polarization of pro-repair macrophages by secreting sFGL2 into the endometriotic milieu. Commun Biol. 4(1): 499. |
Background
Fibrinogen-like protein 2 (FGL2) is a member of the fibrinogen-like protein family and possesses important regulatory functions in both innate and adaptive immune responses. Fibrinogen-like protein 2 (FGL2) exists in both soluble and membrane forms. Soluble fibrinogen-like protein 2 (sFGL2) has been recently identified as a novel effector molecule of Tregs and plays a pivotal role in regulating both innate and adaptive immunity. FGL2 mediates its immunosuppressive activity by binding to inhibitory FcγRIIB (CD32B) receptors expressed by antigen presenting cells (APC), including dendritic cells (DC) and B cells, and thus sFGL2 may inhibit the maturation of DC, resulting in the suppression of effector T cell responses and inducing apoptosis of B cells.
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4.6 ★★★★★
Based on 5 reviews
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Product Reviews
★★★★★ 5
Best thing ever!
Color: Lavender Luxury
These are the best thing ever! Put your favorite foot balm on then cover your heels with these socks and go to bed. You’ll wake up with the softest feet and no cracked heels!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 16, 2026
★★★★★ 4
Works well if you wear them every day
Color: Lavender Luxury, Color: Lavender Luxury
These heel socks do work, but you need to be consistent and patient. The socks are soft with a gel lining on the inside that basically traps your body heat and moisture—kind of like a mini spa for your feet. My heels felt noticeably softer after just one hour of wearing them.
That said, I don’t love sleeping with socks on, so it took me two nights to get used to them. I even took them off the first night because I couldn’t stand the feeling. After five nights of use with nightly exfoliating, my heels are definitely softer, but still cracked in some areas. I’m hoping they keep improving with continued use.
If you stick with it and exfoliate regularly, these socks definitely help soften rough skin. Not a miracle fix overnight, but a helpful tool for healing cracked heels.
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Reviewed in the United States on June 6, 2025
★★★★★ 5
Amazing product
Color: Teal Tranquility
Great product worked within a week of consistent use
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Reviewed in the United States on April 23, 2026
★★★★★ 5
Comfortable
Color: Teal Tranquility
Love these. They do the job!
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Reviewed in the United States on May 8, 2026
★★★★★ 5
A must for the summer
Color: Mellow Moon
I was a bit skeptical about these after seeing on tik toc, but they really work. I have not had a pedicure in months and with these my feet remain smooth.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 26, 2026
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